'We will never solve AIDS without a thorough examination of non HIV AIDS. That’s the lesson here.'
A large section of my upcoming book 'CascAIDS: the shocking true story of how a tiny elite of scientists, medics, public health officials, activists and celebrities faked a global pandemic.'
In June 1981, 4 days before the initial MMWR report it was reported that 'Acute CMV infection is associated with a reversal in the normal ratio of helper to suppressor T lymphocytes with relative and absolute decreases in T helper cells and corresponding increases in T suppressor cells.' The precise immune deficiency marker seen in AIDS cases.
full title should have been 'Pneumocystis Pneumonia, CMV -- Los Angeles.'
'In the period October 1980-May 1981, 5 young men, all active homosexuals, were treated for biopsy-confirmed Pneumocystis carinii pneumonia at 3 different hospitals in Los Angeles, California. Two of the patients died. All 5 patients had laboratory-confirmed previous or current cytomegalovirus (CMV) infection and candidal mucosal infection. Case reports of these patients follow.'
The reason this obvious explanation was discarded and dismissed by the KSOI Task Force was due to Don Francis and his conviction from the get-go that AIDS was caused by a retrovirus. As the very earliest 'early decider' in the 'HIV causes AIDS' 'Availability cascade' Francis influenced Jim Curran, Myron Essex, Robert Gallo, Rozembaum in Paris to pursue his single-retrovirus cause of AIDS.
I would love to share this information more widely and I hope you will help me do so.
Of course CMV by itself couldn't do all that damage, cue the immune system burnout theory. Whilst Gottlieb according to Shilts p43 immediately blamed a t-cell killing virus for the fall off in T4 numbers, what many believed is that the t-cell production line, bone marrow / thymus was slowed down and finally halted by immune system burn out. Many papers were produced connecting AIDS with thymus atrophy ie
'Acquired immunodeficiency syndrome (AIDS) is a severe disorder of unknown etiology and pathogenesis, predominantly affecting homosexual males and other high-risk groups and characterized by profound alterations in T-lymphocyte function. The authors have examined thymus tissue from 14 patients who died of AIDS and compared the results with findings in five control groups: healthy age-matched controls, elderly individuals, patients with chronic or debilitating illnesses other than AIDS, infants with conditions causing “stress atrophy,” and patients with myasthenia gravis. The AIDS group included 11 homosexual males, 1 Haitian, 1 homosexual who was also a drug abuser, and a 10-month-old infant believed to have contracted AIDS following blood transfusion. All the AIDS cases showed marked thymus involution with severe depletion of both lymphocytes and epithelial elements. The latter component consisted primarily of thin cords and nests of primitiveappearing epithelial cells that could be defined by positive immunohistochemical staining for keratin. Many cases showed a variable plasma cell infiltration, and the majority exhibited distinct vascular changes in the form of hyalinization and/or onion-skin patterns, primarily in the adventitia. Most striking of all was the marked paucity of Hassall’s corpuscles; four patients had none at all, while in the other ten patients all the Hassall’s corpuscles were calcified. These changes were far more extensive than those seen in any of the control groups, which retained most of their complement of Hassall’s corpuscles even in the face of marked overall involution. The physiologic function of Hassall’s corpuscles is not known, but recent immunohistochemical studies have implicated them in the synthesis of “facteur thymique serique” (FTS, thymulin) and other thymic hormones known to play a role in regulating Thelper and suppressor cell activity. It is conceivable that the extensive destruction of Hassall’s corpuscles observed in AIDS may be a crucial element in the pathogenesis of this syndrome.'
These papers were common until the mid 80s but disappeared once the HIV causes AIDS narrative became the orthodox dogma and Fauci took control of the research paper purse strings and papers had to acknowledge the primacy of HIV as the cause of AIDS.
As for CMV, immunosuppression and the thymus, this paper explains the link
'The capacity of CMV to cause high-level, antigen-specific and perhaps non–antigen-specific inflammatory responses is well known. Theoretically, the lack of a thymus and the presence of CMV may result in sustained inflammation and high-level T cell turnover, resulting eventually in an exhausted ability of an already compromised immune system to maintain a normal healthy adaptive immune system.'
AIDS = immune system burnout / exhaustion of the thymus caused by viral infection overload.
There is what I label TAC, the 'Thymus Atrophy Cycle.' The thymus becomes worn down by repeated infection, fewer t4 cells are produced, opportunistic infections attack the thymus, it gets further worn down, fewer t4 are produced.
'The acquired immune deficiency syndrome (AIDS) apparently represents a progressive and irreversible loss of cell-mediated immunity (Fauci, 1983). This may be in part a result of an organ-specific immune complex attack on the thymus gland.
The study of the AIDS thymus glands revealed marked histological abnormalities with destruction of the normal architecture. There appeared to be a systematic destruction of Hassall' s corpuscles and alteration in the appearance of the
'An Epidemic of Cytomegalovirus Disease in a Renal Transplant Population' based on reserach pf patients from 1970-71
'All patients were ill with a clinically unique syndrome, manifested by the occurrence of fever 40 days after transplant, persistence of fever for four to six weeks, the development of interstitial pneumonitis.'
Cytomegalovirus: Clinical Virological Correlations in Renal Transplant Recipients
'The severely immunosuppressed patient cannot make an antibody response, he may be further immunosuppressed by the viral infection, and is susceptible to sequential opportunistic infections leading to death.'
'INFECTIOUS DISEASE SYNDROMES ATTRIBUTABLE TO CYTOMEGALOVIRUS'
'Because of the ubiquity of cytomegalovirus (CMV) infection among renal transplant patients, the correlation between CMV isolation and clinical events is often difficult. In this prospective study, clinical CMV disease was diagnosed in 26 of 68 patients (38%) that received transplants between 1974 and 1976 on the basis of viral isolation and/or >4-fold rise in complement-fixing antibody in patients with an unexplained febrile illness of >5 days' duration. All CMV syndromes began 1 to 4 months post-transplant, persisting up to 23 weeks thereafter (mean duration of symptoms was 19 days). Although CMV was observed in some instances to cause only prolonged fever (10 patients) or hepatitis (4 patients), its most important effects were pneumonia (9 patients) and profound leukopenia (8 patients). Three patterns of pneumonia were observed: bilateral interstitial pneumonia (3 patients), unilateral focal consolidation (1 patient) (both attributable to CMV alone), and diffuse bilateral pneumonia attributable to CMV and superinfecting microorganisms (5 patients). These last patients had CMV-induced leukopenia of >1 week's duration at onset of superinfection, and all died. The 4 patients without leukopenia did not develop superinfection, and all survived. Two other renal transplant recipients died of infection during this period, both with CMV, leukopenia, and Listeria monocytogenes sepsis. The major infectious disease importance of CMV appears to be its effects on the respiratory tract and systemic host defense in predisposing to fatal superinfection.'
Read that last sentence again: 'The major infectious disease importance of CMV appears to be its effects on the respiratory tract and systemic host defense in predisposing to fatal superinfection.'
Again this is AIDS! Described in 1977! Why were papers like this ignored by the CDC? Don Francis said 'CMV never killed anybody.' He was 100% wrong.
Read more about all of this in
'CASCAIDS: The shocking true story of how a tiny elite of scientists, medics, public health officials, activists and celebrities faked a global pandemic.' See https://cascades.substack.com/ for regular updates of this new, work in progress, non-fiction book about the 'HIV causes AIDS' scam.
Hi Rebecca.
'We will never solve AIDS without a thorough examination of non HIV AIDS. That’s the lesson here.'
A large section of my upcoming book 'CascAIDS: the shocking true story of how a tiny elite of scientists, medics, public health officials, activists and celebrities faked a global pandemic.'
https://cascades.substack.com/p/cascaids
is given to what I believe to be the obvious explanation for AIDS in homosexual males in the early 80s, CMV.
Why CMV?
It had the means: a close association between it and PCP pneumonia had been recognized for 20 years before 1981. https://www.penroseinquiry.org.uk/finalreport/pdf/LIT0013977.PDF
A close association between CMV and KS had been noted from the early 1970s, https://academic.oup.com/jnci/article-abstract/49/6/1495/1024861?redirectedFrom=fulltext&login=false
In June 1981, 4 days before the initial MMWR report it was reported that 'Acute CMV infection is associated with a reversal in the normal ratio of helper to suppressor T lymphocytes with relative and absolute decreases in T helper cells and corresponding increases in T suppressor cells.' The precise immune deficiency marker seen in AIDS cases.
https://pubmed.ncbi.nlm.nih.gov/6262407/
CMV had the opportunity.
In early 1981 a paper reported 90%+ of sexually active homosexual males had been infected by CMV, a life-long herpes virus
https://academic.oup.com/jid/article-abstract/143/2/188/815104?redirectedFrom=fulltext&login=false
The very first June 1981 MMWR report https://www.cdc.gov/mmwr/preview/mmwrhtml/lmrk077.htm
full title should have been 'Pneumocystis Pneumonia, CMV -- Los Angeles.'
'In the period October 1980-May 1981, 5 young men, all active homosexuals, were treated for biopsy-confirmed Pneumocystis carinii pneumonia at 3 different hospitals in Los Angeles, California. Two of the patients died. All 5 patients had laboratory-confirmed previous or current cytomegalovirus (CMV) infection and candidal mucosal infection. Case reports of these patients follow.'
The reason this obvious explanation was discarded and dismissed by the KSOI Task Force was due to Don Francis and his conviction from the get-go that AIDS was caused by a retrovirus. As the very earliest 'early decider' in the 'HIV causes AIDS' 'Availability cascade' Francis influenced Jim Curran, Myron Essex, Robert Gallo, Rozembaum in Paris to pursue his single-retrovirus cause of AIDS.
I would love to share this information more widely and I hope you will help me do so.
Regards,
Paul
Of course CMV by itself couldn't do all that damage, cue the immune system burnout theory. Whilst Gottlieb according to Shilts p43 immediately blamed a t-cell killing virus for the fall off in T4 numbers, what many believed is that the t-cell production line, bone marrow / thymus was slowed down and finally halted by immune system burn out. Many papers were produced connecting AIDS with thymus atrophy ie
https://academic.oup.com/ajcp/article-abstract/84/1/85/1826736?redirectedFrom=fulltext
'Acquired immunodeficiency syndrome (AIDS) is a severe disorder of unknown etiology and pathogenesis, predominantly affecting homosexual males and other high-risk groups and characterized by profound alterations in T-lymphocyte function. The authors have examined thymus tissue from 14 patients who died of AIDS and compared the results with findings in five control groups: healthy age-matched controls, elderly individuals, patients with chronic or debilitating illnesses other than AIDS, infants with conditions causing “stress atrophy,” and patients with myasthenia gravis. The AIDS group included 11 homosexual males, 1 Haitian, 1 homosexual who was also a drug abuser, and a 10-month-old infant believed to have contracted AIDS following blood transfusion. All the AIDS cases showed marked thymus involution with severe depletion of both lymphocytes and epithelial elements. The latter component consisted primarily of thin cords and nests of primitiveappearing epithelial cells that could be defined by positive immunohistochemical staining for keratin. Many cases showed a variable plasma cell infiltration, and the majority exhibited distinct vascular changes in the form of hyalinization and/or onion-skin patterns, primarily in the adventitia. Most striking of all was the marked paucity of Hassall’s corpuscles; four patients had none at all, while in the other ten patients all the Hassall’s corpuscles were calcified. These changes were far more extensive than those seen in any of the control groups, which retained most of their complement of Hassall’s corpuscles even in the face of marked overall involution. The physiologic function of Hassall’s corpuscles is not known, but recent immunohistochemical studies have implicated them in the synthesis of “facteur thymique serique” (FTS, thymulin) and other thymic hormones known to play a role in regulating Thelper and suppressor cell activity. It is conceivable that the extensive destruction of Hassall’s corpuscles observed in AIDS may be a crucial element in the pathogenesis of this syndrome.'
These papers were common until the mid 80s but disappeared once the HIV causes AIDS narrative became the orthodox dogma and Fauci took control of the research paper purse strings and papers had to acknowledge the primacy of HIV as the cause of AIDS.
As for CMV, immunosuppression and the thymus, this paper explains the link
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2752092/#:~:text=Theoretically%2C%20the%20lack%20of%20a,normal%20healthy%20adaptive%20immune%20system.
'The capacity of CMV to cause high-level, antigen-specific and perhaps non–antigen-specific inflammatory responses is well known. Theoretically, the lack of a thymus and the presence of CMV may result in sustained inflammation and high-level T cell turnover, resulting eventually in an exhausted ability of an already compromised immune system to maintain a normal healthy adaptive immune system.'
AIDS = immune system burnout / exhaustion of the thymus caused by viral infection overload.
There is what I label TAC, the 'Thymus Atrophy Cycle.' The thymus becomes worn down by repeated infection, fewer t4 cells are produced, opportunistic infections attack the thymus, it gets further worn down, fewer t4 are produced.
Here is scientific conformation of this theory:
https://link.springer.com/chapter/10.1007/978-1-4684-4745-3_5
'The acquired immune deficiency syndrome (AIDS) apparently represents a progressive and irreversible loss of cell-mediated immunity (Fauci, 1983). This may be in part a result of an organ-specific immune complex attack on the thymus gland.
The study of the AIDS thymus glands revealed marked histological abnormalities with destruction of the normal architecture. There appeared to be a systematic destruction of Hassall' s corpuscles and alteration in the appearance of the
thymic epithelial cells.'
Regards,
Paul
Anyone who doubts that CMV had the means to be a major factor, perhaps the main factor should read this.
https://link.springer.com/chapter/10.1007/978-1-4613-2185-9_6
'Cytomegalovirus Infection and the Immune System'
The interaction of human cytomegalovirus (CMV) with the immune system
offers an unusual display of findings. CMV infection produces changes in
the immune network which can result in depression of immune function.
(If) there is an environment conducive to serious CMV infections, CMV functions as an opportunistic infectious agent, a double interaction.'
In short CMV is both cause and effect of immune system activity. Again, another cycle is implements.
CMV infection - immune system reaction - CMV infection grows - immune system reaction - opportunistic infections develop.
In the 1970s 3 papers produced in respect of kidney transplant patients showed the lethal effect of CMV.
The first one - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1129295/pdf/westjmed00305-0023.pdf
'An Epidemic of Cytomegalovirus Disease in a Renal Transplant Population' based on reserach pf patients from 1970-71
'All patients were ill with a clinically unique syndrome, manifested by the occurrence of fever 40 days after transplant, persistence of fever for four to six weeks, the development of interstitial pneumonitis.'
The second one - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1344157/pdf/annsurg00296-0257.pdf
Cytomegalovirus: Clinical Virological Correlations in Renal Transplant Recipients
'The severely immunosuppressed patient cannot make an antibody response, he may be further immunosuppressed by the viral infection, and is susceptible to sequential opportunistic infections leading to death.'
This is exactly what happened with AIDS patients!
The third one: https://journals.lww.com/transplantjournal/Abstract/1977/12000/INFECTIOUS_DISEASE_SYNDROMES_ATTRIBUTABLE_TO.10.aspx
'INFECTIOUS DISEASE SYNDROMES ATTRIBUTABLE TO CYTOMEGALOVIRUS'
'Because of the ubiquity of cytomegalovirus (CMV) infection among renal transplant patients, the correlation between CMV isolation and clinical events is often difficult. In this prospective study, clinical CMV disease was diagnosed in 26 of 68 patients (38%) that received transplants between 1974 and 1976 on the basis of viral isolation and/or >4-fold rise in complement-fixing antibody in patients with an unexplained febrile illness of >5 days' duration. All CMV syndromes began 1 to 4 months post-transplant, persisting up to 23 weeks thereafter (mean duration of symptoms was 19 days). Although CMV was observed in some instances to cause only prolonged fever (10 patients) or hepatitis (4 patients), its most important effects were pneumonia (9 patients) and profound leukopenia (8 patients). Three patterns of pneumonia were observed: bilateral interstitial pneumonia (3 patients), unilateral focal consolidation (1 patient) (both attributable to CMV alone), and diffuse bilateral pneumonia attributable to CMV and superinfecting microorganisms (5 patients). These last patients had CMV-induced leukopenia of >1 week's duration at onset of superinfection, and all died. The 4 patients without leukopenia did not develop superinfection, and all survived. Two other renal transplant recipients died of infection during this period, both with CMV, leukopenia, and Listeria monocytogenes sepsis. The major infectious disease importance of CMV appears to be its effects on the respiratory tract and systemic host defense in predisposing to fatal superinfection.'
Read that last sentence again: 'The major infectious disease importance of CMV appears to be its effects on the respiratory tract and systemic host defense in predisposing to fatal superinfection.'
Again this is AIDS! Described in 1977! Why were papers like this ignored by the CDC? Don Francis said 'CMV never killed anybody.' He was 100% wrong.
Read more about all of this in
'CASCAIDS: The shocking true story of how a tiny elite of scientists, medics, public health officials, activists and celebrities faked a global pandemic.' See https://cascades.substack.com/ for regular updates of this new, work in progress, non-fiction book about the 'HIV causes AIDS' scam.
Regards,
Paul
The Lion Diet cures inflammation of all kinds.
I’ve heard about this, but I’m not really familiar with it. I do know that drastic dietary changes can be really helpful with chronic illness.