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Christoph.'s avatar

The HIV hypothesis really has gotten itself into a corner. I'm sure the scientific establishment has convoluted theories about why the body's own neutralizing antibodies don't protect from supposed HIV infection, but their synthetically derived ones somehow would. How are they determining that a vaccine trial fails? A few years ago I read a story about a 'rare' PrEP failure I think in the San Francisco area. A guy had been on it for a couple years, and during the frequent testing there was a 'blip' of a positive on one test. So they ran another test and it was negative. But wanting to hedge their bets they ran another and it was positive. All the tests were in disagreement (antibody and genetic). So they literally just threw up their hands and decided to call him positive. I'm guessing it didn't cross their minds to question the veracity of the tests altogether.

But the big problem as I see it is that PrEP is seen as safe and effective. When you look up side effects they're always downplayed as being initial short-term ones during an adjustment period of several weeks or maybe a month. Bone loss isn't going to show up in that short time frame and so guys think that if they've made it past this early phase with no or little issues they're ok. How often are doctors testing for bone loss in men they see as not being at risk? The way I see is that young healthy guys who don't feel any negatives now taking these drugs are long-term borrowing from the future in terms of their health. This is also the case with statins, psychiatric drugs and just about any long-term pharmaceutical.

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Matt Irwin MD's avatar

Fears of a positive Covid test sank even farther in 2023. I have even started telling people that they can get five days off work if they just test themselves right after getting a vaccine or in the middle of any inflammatory illness or allergic reaction. I considered marketing a test that will always be positive every time you use it - this guarantees a five day break. And if symptoms continue for a few days after that, who’s going to complain about a brief extension?

The fears of “Testing positive“ had already sunk to incredible lows after the initial tsunami of infectious fears came through starting in March 2020, And hopefully this lesson will protect us as we go forward.

The covid experience has offered an opportunity to re-examine things like hiv, and I’m grateful your work has come back to the light, Rebecca. Hopefully we can use this new awareness to help people take care of each other when they’re ill without quarantines, isolation protocols, etc.

That said, taking five days off can be good for you especially if used wisely. - a spiritual retreat might be a bit better than a five day binge, but who am I to judge, lest I also be judged? 😇

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